Human body systems crossword: crossword puzzle for Grade 8, page 1 preview

Crossword puzzle · Science

Human body systems crossword · Grade 8

Solve a crossword of up to 15 words about human body systems from short definition clues. Builds vocabulary, spelling and reading for meaning.

Grade 8 · ages 13 to 14
Hard
15 to 20 minutes
1 page
Free

Goes with the game Body Explorer.

The answer key is a separate page for grown-ups. Sign in to download it.

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The crossword clues

Directions: Read each clue and write the answer in the grid, one letter in each box.

Across
3 System that defends the body against germs
6 System of glands that release hormones into the blood
8 Blood vessel that carries blood back to the heart
9 System of bones that supports and protects the body
12 Blood vessel that carries blood away from the heart
13 System that breaks food into nutrients the body can absorb
14 System that brings in oxygen and removes carbon dioxide
Down
1 The body's balancing act that keeps conditions inside steady
2 Protein that speeds up chemical reactions, such as digestion
4 System that moves the body by contracting and relaxing
5 Nerve cell that carries electrical signals
7 System that pumps blood through the heart and blood vessels
10 System, including the kidneys, that removes wastes
11 System of brain, spinal cord and nerves that carries signals

What your child practices

Your child builds vocabulary, spelling and reading for meaning.

Grades and ages: Grade 8, ages 13 to 14
Time: About 15 to 20 minutes
Subject: Science
Level: Hard for Grade 8
Answer key: Yes, for grown-ups who sign in
Printing: 1 page, US Letter or A4, low-ink option
Updated: October 15, 2026

How to use it

Read the first across clue together so the format is clear. Use a pencil so mistakes rub out easily, and check every answer at the end. It is one of the harder sheets for Grade 8, best once the basics of the topic are secure.

An answer key comes with it as a separate page that grown-ups download after signing in.

Tip for grown-ups: Use the letter count after each clue and any crossing letters when a clue gets stuck.

Done on paper? A grown-up can record it on the child's page in PlayOwl; downloading alone doesn't count as finished.